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TGIF2 Polyclonal Antibody, 100ul Cryopreservation The preproprotein encoded by CACNA2D1

SKU: 11306813460

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TGIF2 Polyclonal Antibody, 100ul Cryopreservation The preproprotein encoded by CACNA2D1The protein encoded by this gene is a DNA binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta responsive genes. This gene is amplified and over expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read through transcription also exists between this gene and the

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Description

The preproprotein encoded by CACNA2D1 (calcium voltage-gated channel auxiliary subunit alpha2delta 1) is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex

The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus

ACVR1B encodes an activin A type IB receptor

Casein kinase I isoform alpha-like (CSNK1A1L) is a 337 amino acid protein that shares a high degree of sequence similarity with the alpha isoform of casein kinase 1

EPS8L2 encodes a member of the EPS8 gene family

TGIF2 Polyclonal Antibody, 100ul Cryopreservation The preproprotein encoded by CACNA2D1The protein encoded by this gene is a DNA binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta responsive genes. This gene is amplified and over expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read through transcription also exists between this gene and the

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