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10.1038/nm.2399 65 JafariM.MousaviS

Musculoskeletal disorders, including tendinopathy, sarcopenia, osteoarthritis and osteoporosis, represent a major and growing global health burden, with osteoarthritis affecting 32.5 million adults in the United States, osteoporosis affecting 8.4-17.7% of middle-aged and elderly adults and nearly half of skeletal muscle mass being lost by the age of 80 years due to sarcopenia (1,2), particularly in aging populations (3)

These findings are significant because they are the first to show that encapsulating an MVM supplement with liposomes can influence the pharmacokinetic (PK) profile of multiple vitamins and minerals present in the supplement, thereby impacting the availability of nutrients

In some cases, the necessary preparation imposes a stress on the sample, which could modify the factor being measured

These structures were crushed, placed in tubes, and homogenized with phosphate buffer (0.1 M