HUWE1 Polyclonal Antibody, 20ul Variant Libraries This protein is highly similar

This protein is highly similar to Saccharomyces cerevisiae Cdc 42

This polymorphism is also associated with the occurrence of the splice variant GNB3-s

and tumor biology

and is found in a cluster of five alpha subunit genes on chromosome 2

a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules

HUWE1 Polyclonal Antibody, 20ul Variant Libraries This protein is highly similarThis gene encodes a protein containing a C terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2 related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with